Clinical Observation on Method of Soothing Liver and Detoxification in the Treatment of Hyperthyroidism Due to Liver-spleen Imbalance

CAO Mingming; LIN Jianliang

doi:10.14033/j.cnki.cfmr.2025.17.006

Abstract：Objective:To observe the clinical effect of the method of soothing liver and detoxification in the treatment of hyperthyroidism due to liver-spleen imbalance.Method:A total of 112 patients with hyperthyroidism due to liver-spleen imbalance who treated in the Dezhou Lingcheng District Traditional Chinese Medicine Hospital from February 2021 to June 2023 were selected,and they were randomly divided into the control group(56 cases)and the study group(56 cases)using the random number table.The control group was given conventional treatment,while the study group was given conventional treatment combined with the method of soothing liver and detoxification,both groups were treated continuously for 3 months.The clinical efficacy,clinical symptom scores and serum indicators before and after treatment,and adverse reactions in two groups were compared.Result:The total effective rate in the study group was significantly higher than that in the control group(91.07%vs 75.00%),the difference was statistically significant(字2=5.134,P<0.05);after 3 months of treatment,the scores of poor appetite,fatigue,and throat discomfort in two groups were lower than those before treatment,the study group showed lower scores than those in the control group,the differences were statistically significant(P<0.05);after 3 months of treatment,the levels of thyroglobulin antibodies(TGAb),thyroid-stimulating hormone(TSH)and thyroid peroxidase antibodies(TPOAb)in both groups were lower compared with before treatment,while the levels of free triiodothyronine(FT3)and free thyroxine(FT4)were higher compared with before treatment,the study group showed a greater improvement than those in the control group,the differences were statistically significant(P<0.05);the incidence of adverse reactions in the study group was lower than that in the control group(3.57%vs 16.07%),the difference was statistically singnificant(字2=4.940,P<0.05).Conclusion:The method of soothing liver and detoxification is effective in the treatment of hyperthyroidism due to liver-spleen imbalance,it can alleviate clinical symptoms,regulate serum indicators,and does not increase adverse reactions.