Application of Gemstone Spectral CT and Dynamic Contrast Enhanced Magnetic Resonance Imaging in the Diagnosis of Sacroiliac Joint Bone Marrow Edema and Activity in Early Ankylosing Spondylitis

YIN Tianbao; PENG Chengchu; YANG Bin

doi:10.14033/j.cnki.cfmr.2025.12.019

Abstract：Objective:To analyze the application value of gemstone energy spectrum CT and dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in the diagnosis of bone marrow edema and activity in the sacroiliac joint of early ankylosing spondylitis.Method:From October 2022 to October 2023,103 patients with early ankylosing spondylitis(AS)admitted to the Third People's Hospital of Huizhou City were selected as the study objects and randomly divided into active group and stable group,with 56 cases in the active group and 47 cases in the stable group.Gemstone energy spectrum CT and DCE-MRI were performed in both groups.The bone marrow edema and activity of the sacroiliac joint were evaluated by Bath Ankylosing Spondylitis Disease Activity Index(BASDA),and the results of gemstone energy spectrum CT and DCE-MRI were compared between the two groups.Result:The water-HAP concentration and extravascular extracellular space volume fraction(Ve),rate contant(Kep)and volume transfer contant(Ktrans)in the bone marrow of the sacroiliac joint were higher in the active group than in the stable group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that the water-HAP concentration in the bone marrow of the sacroiliac joint in gem energy imaging CT was correlated with the bone marrow edema and activity of the sacroiliac joint Ve,Kep and Ktrans in the DCE-MRI parameters,and the difference was statistically significant(P<0.05).The ROC curve showed that the concentration of water-hap in the bone marrow of the sacroiliac joint in the sapphire energy spectrum CT and the AUC of the sacroiliac joint Ve,Kep and Ktrans in the parameters of DCE-MRI were of certain diagnostic value in the diagnosis of bone marrow edema and activity of the sacroiliac joint in early ankylost spondylitis.Conclusion:In early patients with ankylosing spondylitis,gem energy spectrum CT and DCE-MRI parameters are closely related to sacroiliac joint bone marrow edema and activity,and have certain diagnostic value,providing new reference for the clinical diagnosis and treatment of early ankylosing spondylitis.