Anesthetic Effect of Different Doses of Alfentanil and Dezocine in Painless Abortion Surgery

HUANG Yong; SHI Bosheng

doi:10.14033/j.cnki.cfmr.2025.04.017

Abstract：Objective:To evaluate the anesthetic effect of different doses of Alfentanil combined with Dezocine and Propofol in painless abortion surgeries.Method:This study prospectively selected 71 patients who underwent painless abortion in Nantong City Traditional Chinese Medicine Hospital from February 2023 to February 2024 as research objects.They were divided into Dezocine group(receiving Dezocine combined with Propofol),low-dose group(low-dose Afentanil combined with Propofol)and high-dose group(high-dose Afentanil combined with Propofol)by random number table method.The hemodynamics[heart rate(HR)and mean arterial pressure(MAP),systolic blood pressure(SBP),diastolic blood pressure(DBP)]before anesthesia induction(T0),before administration(T1),predilation(T2),postdilation(T3),after recovery(T4)and analgesic effects[visual analogue scale(VAS)score at 3 h,12 h,24 h after surgery],quality of recovery were compared among the three groups.Result:There were significant differences in HR,MAP,SBP and DBP among the three groups at different time points(P<0.05).The induction time,recovery time and discharge time in the high-dose group were shorter than those in the low-dose group and Dezocine group,and the differences were statistically significant(P<0.05).The VAS scores of 3 h,12 h and 24 h after surgery in the high-dose group were lower than in the low-dose group and Dezocine group,and the differences were statistically significant(P<0.05).Conclusion:Using Alfentanil as an adjunctive anesthetic in painless abortion surgeries,particularly at higher doses,can effectively improve perioperative hemodynamic stability,provide superior postoperative analgesic effects,and enhance recovery quality.Therefore,it is recommended to consider an appropriate dose of Alfentanil to optimize anesthetic management in painless abortion surgeries.