Effect of Amlodipine Besylate Tablets Combined with Bushen Huoxue Decoction in Patients with Hypertensive Nephropathy

ZHU Lu; ZENG Jianbin

doi:10.14033/j.cnki.cfmr.2025.01.016

Abstract：Objective:To explore the effect of Amlodipine Besylate Tablets combined with Bushen Huoxue Decoction on hypertensive nephropathy patients. Method:A total of 80 patients with hypertensive nephropathy admitted to Jiujiang Hospital of Traditional Chinese Medicine from October 2021 to March 2023 were selected. According to the odd-even number of patients,the singular patients were included in the reference group,and the even-number patients were included in the study group,with 40 cases in each group. The reference group was given Amlodipine Besylate Tablets,and the study group added Bushen Huoxue Decoction on this basis. Blood pressure levels,renal function indicators and traditional Chinese medicine syndrome scores before and after treatment of the two groups were compared. Result:After treatment,the diastolic blood pressure and systolic blood pressure in the study group were lower than those in the reference group,and the difference was statistically significant (P<0.05). After treatment,the levels of blood urea nitrogen,creatinine and 24 h urinary microalbumin in the study group were lower than those in the reference group,the differences were statistically significant (P<0.001). After treatment,the scores of traditional Chinese medicine symptoms in the study group were lower than those in the reference group,and the difference was statistically significant (P<0.001). Conclusion:The combination of Amlodipine Besylate Tablets and Bushen Huoxue Decoction can effectively regulate blood pressure levels,improve renal function damage,and alleviate clinical symptoms in the treatment of hypertensive nephropathy.