Effect of Jianpi Shengxue Granules Combined with Ferrous Succinate in the Treatment of Patients with Iron Deficiency Anemia during Pregnancy

WANG Xiaofang; WANG Furong

doi:10.14033/j.cnki.cfmr.2025.01.006

Abstract：Objective:To observe the effect of Jianpi Shengxue Granules combined with Ferrous Succinate in the treatment of patients with iron deficiency anemia during pregnancy. Method:A total of 128 patients with iron deficiency anemia during pregnancy treated in Jintai Hospital in Baoji City from January to December 2023 were selected. They were divided into control group (n=64) and observation group (n=64) according to random number table method. The control group was treated with Ferrous Succinate,and the observation group was treated with Jianpi Shengxue Granules on the basis of the control group. The clinical efficacy,blood biochemical and iron metabolism indexes before and after medication,pregnancy outcome and adverse reactions were compared between the two groups. Result:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant (P<0.05). After treatment,red blood cell count (RBC),mean red blood cell hemoglobin concentration (MCHC),hematocrit (HCT) and hemoglobin (Hb) levels in both groups were increased,and RBC,MCHC,HCT and Hb levels in observation group were higher than those in control group,the differences were statistically significant (P<0.05). After treatment,the levels of ferritin (SF),transferrin (TRF),iron concentration (SI) and iron regulating hormone (HEPC) in both groups were increased,and the levels of SF,TRF,SI and HEPC in observation group were higher than those in control group,the differences were statistically significant (P<0.05). The incidences of preterm birth,cesarean section,puerperal infection,postpartum hemorrhage,low birth weight infants and neonatal asphyxia in observation group were lower than those in control group,and the differences were statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion:The application of Ferrous Succinate combined with Jianpi Shengxue Granules in the treatment of iron-deficiency anemia in pregnancy can effectively regulate iron metabolism,improve blood biochemical indexes,reduce adverse pregnancy outcomes,with definite clinical effect and drug safety.