Relationship between Mid Late Stage Pregnancy Weight Gain Rate and Glycolipid Metabolism and Neonatal Outcomes in Pregnant Women with GDM

WU Huiping

doi:10.14033/j.cnki.cfmr.2024.32.018

Abstract：Objective:To analyze the relationship between mid late stage pregnancy weight gain rate and glycolipid metabolism and neonatal outcomes in pregnant women with gestational diabetes mellitus(GDM).Method:A total of 290 pregnant women with GDM admitted to Maternal and Child Health Care Hospital,Fuzhou Second General Hospital from January to August 2023 were selected.According to the weight gain rate in the mid late stage of pregnancy,they were divided into fast group(103 cases),normal group(142 cases)and slow group(45 cases).All pregnant women were tested for glycolipid metabolism.Glucose metabolism indexes,lipid metabolism indexes and neonatal outcomes were compared among the three groups.Result:Fasting blood glucose(FPG)and glycosylated hemoglobin(HbA1c)levels in the fast group were higher than those in the normal group and the slow group,the differences were statistically significant(P＜0.05).The levels of triglyceride(TG),total cholesterol(TC)and apolipoprotein B(Apo-B)in fast group were higher than those in normal group and slow group,the differences were statistically significant(P＜0.05).The incidence of premature infants in the fast group was lower than that in the slow group,and the incidence of giant infants was higher than that in the slow group and the normal group,the differences were statistically significant(P＜0.05).Conclusion:Excessive weight gain rate in the mid and late stage of GDM pregnant woman can cause abnormal glucose and lipid metabolism,increase the risk of macrosomia,but reduce the incidence of premature babies.