Comparison of Effect of Bone Cement-reinforced Hollow Lateral Hole Screw Fixation and Traditional Pedicle Screw Fixation in the Treatment of Thoracolumbar Spinal Fracture

LU Qihao; ZHOU Yingyong; CHI Kaiyu

doi:10.14033/j.cnki.cfmr.2024.32.009

Abstract：Objective:To compare the effect of bone cement-reinforced hollow lateral hole screw fixation and traditional pedicle screw fixation(PSF)in the treatment of thoracolumbar spinal fracture(SF).Method:The medical records of 120 patients with thoracolumbar SF who admitted to Xiamen Hospital of Traditional Chinese Medicine from June 2020 to June 2023 were retrospectively collected,they were divided into the observation group(bone cement-enhanced hollow lateral hole screw fixation,n=60)and the control group(traditional PSF,n=60)according to different surgical schemes.The surgical effect,imaging indexes(height ratio of anterior edge of injured vertebrae,Cobb's angles of injured vertebrae),vertebral function[Oswestry dysfunction index(ODI)score],bone metabolism indexes[β-collagen degradation product(β-CTX),bone γ-spindle glutamate protein(BGP),bone morphogenetic protein-2(BMP-2)]and incidence of complications were compared between two groups.Result:The excellent and good rate of operation in the observation group was 98.33%,which was higher than 86.67%in the control group,and the difference was statistically significant(P＜0.05);at 6 months after operation,the height ratio of anterior edge of injured vertebrae and the levels of serum BGP and BMP-2 in two groups were higher than those before operation,and the Cobb's angles of injured vertebrae,ODI scores and serum β-CTX levels were lower than those before operation,the height ratio of anterior edge of injured vertebrae and the levels of serum BGP and BMP-2 in the observation group were higher than those in the control group,and the Cobb's angle of injured vertebrae,ODI score and serum β-CTX level were lower than those in the control group,the differences were statistically significant(P＜0.05);the incidence of complications in the observation group was 3.33%,which was lower than 15.00%in the control group,and the difference was statistically significant(P＜0.05).Conclusion:Compared with traditional PSF in the treatment of thoracolumbar SF patients,bone cement-reinforced hollow lateral hole screw fixation can further improve the surgical effect,improve the vertebral function and the level of bone metabolism,promote the recovery of spinal physiological and anatomical structure,and reduce the risk of complications.