Efficacy and Safety of Kaihoujian Spray Combined with Interferon α2b in the Treatment of Pediatric Herpetic Pharyngitis
ZHANG Jinyue
Abstract：Objective:To explore the efficacy and safety of Kaihoujian Spray combined with Interferon α2b in the treatment of pediatric herpetic pharyngitis.Method:A total of 86 children with herpetic pharyngitis admitted to Putian Children's Hospital from November 2021 to November 2023 were selected.All cases were divided into control group and observation group by random number table,43 cases in each group.The control group was given Interferon α2b,and the observation group was treated with Kaihoujian Spray based on the control group.The clinical efficacy,symptom improvement time,symptom score,inflammatory factors,immune function before and after treatment and safety of the two groups were compared.Result:Compared with the control group,the total effective rate of the observation group was higher,the symptom improvement time of the observation group was earlier,the symptom scores,inflammatory levels and CD8+of the observation group were lower,and the CD3+,CD4+,CD4+/CD8+levels of the observation group were higher,the differences were statistically significant (P<0.05).The adverse reactions of two groups were compared,which showed no significant difference (P>0.05).Conclusion:Kaihoujian Spray combined with Interferon α 2b can enhance the therapeutic effect of herpetic pharyngitis,accelerate the regression of symptoms and the decline of inflammation,improve immune function,and have good safety.
Keywords：Herpetic pharyngitisKaihoujian SprayInterferon α2bClinical efficacyInflammatory factorsSafety
Publication Date：2024-11-05
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 30-33 )