Therapeutic Effects of Co-infusion of Platelets and Cryoprecipitation in the Treatment of Patients with Massive Blood Loss:A Meta-analysis
LIN Shu-ting
LAI Dong
LONG Min
Abstract：Objective:To systematically evaluate therapeutic effects of co-infusion of platelets and cryoprecipitation in the treatment of patients with massive blood loss.Method:The domestic lectures were retrieved from databases including CBM,CNKI,Wanfang Database.The meta-analyses were performed with RevMan 5.3 software for 15 randomized controlled trials(RCTs) of 1316 patients.Result:Compared with platelet group,PT,APTT and the average hemostasis time of co-infusion were all significantly shorten(P<0.01),the consumption of suspended red blood cells in 24 h was decreased significantly(P<0.01),and hemostatic efficiency was improved significantly(P<0.01),and post transfusion PLT had no significant changes(P>0.05).Compared with cryoprecipitation group, PT,APTT and the average hemostasis time of co-infusion were all significantly shorten(P<0.01),the consumption of suspended red blood cells in 24 h was decreased significantly(P<0.01),and hemostatic efficiency and post transfusion PLT were improved significantly(P<0.01).Conclusion:Co-infusion overcome the coagulation disorders in patients with massive blood loss,and it is the best method of hemostatic effect.It will win enough time for saving the patient’s precious life.
Keywords：PlateletsCryoprecipitationCo-infusionMassive blood lossMeta-analysis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1-3,4 )