Clinical Observation of Atorvastatin Combined with Traditional Chinese Medicine to Improve the Prognosis of Patients with Chronic Heart Failure

MA Zhao-juan; YUAN Jian-xi

doi:10.14033/j.cnki.cfmr.2016.24.002

Abstract：Objective:To investigate the effect of Atorvastatin combined with traditional Chinese medicine in improving the prognosis of patients with chronic heart failure.Method:100 cases of chronic heart failure patients whose cardiac function NY-HA grade was Ⅱ-Ⅳ grade were randomly divided into the control group (48 cases) and treatment group (52 cases).The control group was treated with conventional treatment,including Digitalis,angiotensin enzyme inhibitor,beta blockers and diuretics.The treatment group on the basis of the control group was given oral Atorvastatin and traditional Chinese medicine.After 8 weeks of treatment,all patients were reviewed.Result:After treatment,the total effective rate of the treatment group was 78.8%,higher than 45.8% of the control group,the difference was statistically significant(P<0.01),and the death rate of the treatment group was significantly lower than that of the control group,the difference was statistically significant(P<0.01).After treatment,the TC,LDL-C and C-reactive protein of the two groups were lower than before treatment,and the left ventricular ejection fraction(LVEF) was higher than before treatment,the TC,LDL-C and C-reactive protein of the treatment group were lower than those of the control group,and the left ventricular ejection fraction(LVEF) was higher than that of the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in the number of times of hospitalization and the total length of stay between the two groups(P>0.05).Conclusion:The application of Atorvastatin combined with traditional Chinese medicine in the treatment of chronic heart failure is simple and effective,it can significantly improve the treatment effect,which has the value of clinical application.