Clinical Analysis of 45 Patients with Nephrotic Syndrome in the Elderly
YANG Li-hua
WEN Zhen
Abstract：Objective:To analyze the diagnosis and treatment of 45 cases of patients with nephrotic syndrome in the elderly(NSIE).Method:The clinical and laboratory data of 45 elderly patients with nephrotic syndrome admitted to our hospital from January 2005 to January 2015 were retrospectively analyzed. Result:For all the 45 patients,membranous nephropathy(MN)(28.9%) was particularly common as a cause of the primary nephrotic syndrome in the elderly,as well as minimal change disease(MCD)(20.0%),while diabetic nephropathy(DN)(33.3%) was as the cause of the secondary nephrotic syndrome.15 cases(33.3%) of the patients displayed impairment of renal function,13 cases(28.9%) displayed hypertension,2 cases(4.4%) displayed thrombus and 5 cases(11.1%) displayed anemia.Through the treatment of steroid,immunosuppressive agent and anticoagulation therapy,the complete remission rate were 33.3% and the partial remission rate was 35.6%,the total effective rate was 68.9%.Conclusion:Current thinking is that infection is the primary factor in the frequent nephrotic syndrome recurrence,there is a high rate of infection and thrombus in nephritic syndrome in the elderly,so the key to the treatment is to prevent thrombus and control infections.
Keywords：Nephrotic syndromeComplicationRenal biopsy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 12-13 )