Clinical Study of 131I Treatment of Fixed Dose and Individual Dose for Graves Disease

doi:10.14033/j.cnki.cfmr.2016.17.002

Abstract：Objective:To study the clinical effect of 131I treatment for Graves disease of fixed dose and individual dose,and the incidence condition of complications.Method:From March 2014 to March 2015,300 cases with Graves in our hospital were selected,and they were divided them into the control group and the research group.The control group was treated with the fixed dose 131I treatment,while the study group was treated with individual dose 131I treatment. And then they were followed up for 6 months,the clinical efficacy and complications incidence rate of the two groups were compared.Result:After treatment, the total effective rate of the control group was 80.67%,while the research group was 79.33%,and the difference between the two groups showed no statistically significant(P>0.05).However,the incidence of hypothyroidism in the control group was 48.67%,while the research group was 33.33%,and the difference between the two groups was statistically significant(P<0.05).Conclusion:The clinical efficacy of the fixed dose and individual dose 131I treatment for Graves disease are very significant,but the individual dose treatment has a low incidence rate of hypothyroidism.Benefit from the higher security,the individual dose 131I treatment is worthy of clinical popularization and application.