The Significance of the Relationship between BNP and Cardiac Output of Heart Failure Patients

JIANG Qin-juan; YAO Lan; ZHANG Cheng-xuan

doi:10.14033/j.cnki.cfmr.2016.1.001

Abstract：Objective:To explore the relationship between BNP and the cardiac output data from Pulse-indicated Continuous Cardiac Output(PiCCO) monitoring in heart failure patients.Method:72 heart failure patients in Peking Union Medical College Hospital and the First People's Hospital of Yueyang City from April 2009 to April 2015 were involved in the retrospective analysis,they were classified as the research group of 38 cases,the control group of 34 cases according to the brain natriuretic peptide(BNP)/the highest normal value of BNP>2 or not,hemodynamic data were recorded through continuous monitoring of PICCO,BNP of every patients were recorded at the same time,we analyzed the relationship between BNP and cardiac output.After 5-days-treatment,the patients were classified as the heart function of Ⅱ-Ⅲ level group of 40 cases,heart function of Ⅳ level group of 32 cases,we analyzed BNP and cardiac output of two group.Result:BNP of the research group (2479.35±302.77)pg/ml was higher than (829.23±38.31)pg/ml of the control group,the cardiac output index and the stroke volume index were lower than those of the control group,there were statistically significant(P<0.05).After 5-days-treatment,there were statistically significant in BNP and cardiac output between the heart function of Ⅱ-Ⅲ level and heart function of Ⅳ level(P<0.05).Conclusion:BNP has a inverse correlation with cardiac output.The more serious of heart function,the lower of cardiac output,the higher of BNP.