Relationship between Adiponectin and Uric acid,Creatinine in Essential Hypertension
TANG Xiao-ming
LI Jie-qi
LI Jian-rong
Abstract：Objective:To examine whether adiponectin affects essential hypertension genetically or biologically.We performed a case-control study to investigate in essential hypertension patients and study the relationship of the uric acid,creatinine to plasma adiponectin concentration.Method:A total of 151 diagnosed cases of essential hypertension(EH group)and 100 normal control(NC group) were enrolled in this study.Plasma adiponectin concentration was measured using an enzyme-linked immunosorbent assay system.Result:The plasma adiponectin concentration in EH group was lower than that of the NC group(P<0.01).The uric acid,creatinine in EH group were highter than those of the NC group(P<0.01).Adiponectin concentration significantly increased with uric acid and creatinine.Conclusion:The plasma adiponectin concentration in essential hypertension group were lower and uric acid,creatinine were highter.Hypoadiponectinemia and hyperuricemia are independent risk factors for hypertension.
Keywords：AdiponectinEssential hypertensionUric acidCreatinine
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 69-70 )