The Effect of Intensive Glucose Control on Postoperative Wound Complications in Total Joint Arthroplsty
YANG Ming-xin
TAN Mei-yun
Abstract：Objective:To investigate the best perioperative glucose level in total joint arthroplasty and the effect of intensive glucose control on postoperative wound complications.Method:A retrospective study was conducted in patients undergoing primary total hip/knee arthroplsty from 2010 to 2014.They were assigned to either intensive glucose control with a blood glucose range of 4.4-7.8 mmol/L,or intermediate glucose control with a blood glucose range of 7.8-10.0 mmol/L.We defined primary end point as the incidence of surgical site infection or periprosthetic joint infection.Result:The number of patients undergoing total joint arthrolasty was 230 cases,165 cases(71.7%) were diabetes mellitus.Perioperatve intensive glucose control produced a significant reduction for the incidence of surgical site infection(1.7% vs 7.3%,P=0.021) and wound leakage(7.5% vs 16.4%,P=0.037).A shorter hospital stay was seen in intensive glucose control group(P=0.018).But intensive glucose control leaded a higher incidence of hypoglycemia(P=0.471).Conclusion:Intensive glucose control could reduce the incidence of postoperative wound complications in total joint arthroplasty,but attention should be paid to the incidence of hypoglycemia.
Keywords：Total joint arthroplastyIntensive glucose controlSurgical site infectionPeriprosthetic joint infection
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 9-11 )