Clinical Effect Analysis of Gemcitabine Combined with Nedaplatin Chemotherapy on Treating 50 Cases of Lung Metastases Transform Nasopharyngeal Carcinom a
Abstract：Objective:To observe and analyze the curative effect of Gemcitabine combined with Nedaplatin chemotherapy on treating 50 cases of lung metastases transform nasopharyngeal carcinoma.Method:90 patients were divided into Gemcitabine combined with Nedaplatin chemotherapy group(GN group) and Cisplatin,5-fluorouracil combined with Docetaxel chemotherapy group(PTF group),the clinical effect and adverse reactions of two groups were retrospective analyzed.Result:The effective rate of GN group was 70.0%,there was obviously improved compared with the PTF group(45.0%),the difference was statistically significant(P<0.05).The two group’s disease control rates were 94.0% and 80.0%,with no significant difference(P>0.05).GN group’s leukopenia and thrombocytopenia grade Ⅲ-Ⅳ incidence rate were lower than than those of PTF group(P<0.05).Conclusion:Gemcitabine combined with Nedaplatin chemotherapy can further improve the prognosis of patients with nasopharyngeal carcinoma with lung metastasis,chemotherapy related toxicity was significantly lower,and it is worthy of clinical application.
Keywords：Nasopharyngeal carcinomaLung metastasisChemotherapy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 8-10 )