Curative Effect Observation of Nifedipine Zyban Combined with Enalaprilat Dispersible Tablets in the Treatment of Hypertensive Heart Disease

LONG Jian-you

doi:10.14033/j.cnki.cfmr.2015.17.013

Abstract：Objective:To investigate the clinical curative effect of Nifedipine Zyban combined with Enalaprilat Dispersible Tablets in the treatment of hypertensive heart disease.Method:120 patients with hypertensive heart disease admitted to our hospital from April 2011 to March 2013 were selected as research objects,they were divided into the control group and the observation group according to the random number table method,60 cases in each group.The control group was given basic drugs for treatment,the observation group was given Nifedipine Zyban combined with Enalaprilat Dispersible Tablets on the basis of the control group,6 weeks for a course of treatment.The clinical efficacy,the changes of heart rate,blood pressure,LVEF value before and after treatment and poor prognosis and mortality after 1 year of treatment between the two groups were observed and compared.Result:The total effective rate of observation group was 91.67%(55/60),which was significantly higher than 65.00%(39/60) of the control group,the difference was statistically significant(χ2=11.0475,P=0.0009).The changes of heart rate,blood pressure and LVEF value in the two groups after treatment were significantly better than before treatment,and the above observation indexes of the observation group were significantly better than the control group,the differences were statistically significant(P<0.05).There were no statistically significant differences in the poor prognosis and mortality after 1 year of treatment between the two groups(P>0.05).Conclusion:Nifedipine Zyban combined with Enalaprilat Dispersible Tablets for the treatment of hypertensive heart disease can obtain good clinical curative effect,and the price is cheap,with good compliance,is particularly worth popularizing in primary hospitals.