Clinical Effect Analysis of Hyperthermia Combined with Interventional Chemotherapy Embolization in the Treatment of Advanced Hepatocellular Carcinom a

LIU Zu-hua

doi:10.14033/j.cnki.cfmr.2015.17.003

Abstract：Objective:To study the clinical effect of hyperthermia combined with interventional chemotherapy embolization in the treatment of advanced hepatocellular carcinoma.Method:80 patients with primary advanced hepatocellular carcinoma admitted to our hospital from June 2008 to February 2012 were selected as research objects,they were divided into the treatment group and the control group according to the random number table method,40 cases in each group.The treatment group was given hyperthermia combined with interventional chemotherapy embolization.The control group only received routine interventional chemotherapy embolization,the four drugs combined with chemotherapy.The clinical efficacy,KPS improvement,pain relief and survival rate during follow-up of the two groups were observed and compared.Result:After treatment,the total effective rate of the treatment group was 75.0%(30/40),which was significantly higher than 40.0%(16/40) of the control group,the total improvement rate of KPS in the treatment group was 80.0%(32/40),which was significantly higher than 50.0%(20/40) in the control group,the pain relief rate of the treatment group was 85.0%(34/40),which was significantly higher than 35.0%(14/40) of the control group,the differences were statistically significant(P<0.05).There were no statistically significant differences in the survival rate of 0.5 year,l year,1.5 years between the two groups(P>0.05),the survival rate of 2 years in the treatment group was 60.0%,which was significantly higher than 25.0%in the control group, the difference was statistically significant(χ2=10.0256,P=0.0015).Conclusion:The clinical efficacy of hyperthermia combined with interventional chemotherapy embolization in the treatment of advanced hepatocellular carcinoma is better than single interventional chemoembolization,it is an effective comprehensive treatment for the treatment of advanced hepatocellular carcinoma,is worthy of clinical application.