Clinical Efficacy of Zoledronic Acid Combined with Chemotherapy in the Treatment of Bone Metastases of Lung Cancer
LI Jia
WU Lin
Abstract：Objective:To investigate the clinical efficacy of Zoledronic Acid combined with chemotherapy in the treatment of bone metastasis of lung cancer.Method:68 cases of lung cancer patients with bone metastasis meeting the inclusion critera were randomly divided into two groups,34 cases in each group.The control group was treated with Zoledronic Acid combined with chemotherapy and the observation group was treated with Zoledronic Acid on the basis of treatment of the control group.The curative efficacy and remission rates of bone metastases of two groups were observed and compared.Result:The effective rate of pain relief in the observation group was 94.12%,and in the control group was 76.47%,the curative efficacy between two groups was significantly different(P<0.05). The remission rate of bone metastases in the observation group was 91.18%,and the control group was 70.59%,the observation group were significantly higher than that of the control group(P<0.05).Conclusion:Zoledronic Acid combined with chemotherapy in the treatment of bone metastasis of lung cancer can effectively reduce the degree of patients’pain,and it is well tolerated,it could be largely improved the quality of life of patients and it will be worthy of further application and promotion.
Keywords：Lung cancerBone metastasisZoledronic AcidChemotherapy
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 20-21 )