Thalassemia and G6PD Deficiency Experiment Exploring Merger Disease G6PD Activity
AO Dong
LI Mei-gui
Abstract：Objective:To analyze the merger thalassemia G6PD deficiency and G6PD activity range to improve national free pre-pregnancy health check diagnosis rate crowd.Method:α-THAL gene,β-THAL gene using(RCR+membrane hybridization) testing,using a variety of electrophoresis found thalassemia validated by pedigree;G6PD deficiency using G6PD/6PGD enzyme direct ratio method combined pedigrees were confirmed.Result:Lightweight α,β and heavy β-thalassemia and G6PD activity HBH patients were 1.5 times normal,two times,>3 times, 2-3 times;approximately 61.4% of the combined thalassemia heterozygotes female G6PD deficiency the G6PD activity was the normal range.Conclusion:G6PD deficiency merger thalassemia heterozygotes women missed their G6PD activity is 61.4%,G6PD activity increased in varying degrees can diagnose different types of thalassemia.
Keywords：ThalassemiaG6PD deficiencyG6PD activity
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 9-10 )