The Role ofβ-blockers in Heart Failure

SU Yong-jun

Abstract：Objective:To research the clinical effect ofβ-blockers in heart failure and arrhythmia.Method:324 patients with chronic heart failure admitted to our hospital from January 2012 to December 2012 were selected,they were divided into the control group,the group A and the group B with the method of random sampling,108 cases in each group.The control group was given Placebo for treatment,the group A was given Metoprolol for treatment,the group B was given Carvedilol for treatment.The death and readmission of the three groups were observed and compared.Result:After 8 weeks of treatment,the sudden death,heart failure caused mortality,cardiovascular mortality,total mortality and readmission rates in group A were 9.26%,8.33%,8.33%,28.70%, 22.22%,those in the group B were 2.78%,1.85%,1.85%,7.41%,12.04%.The observed indices of two groups were significantly lower than the control group, and the above indexes of group B were significantly lower than group A,the differences were statistically significant(P<0.05).Conclusion:β-blockers has the advantage of reducing mortality and readmission rates in the treatment of heart failure and cardiac arrhythmias,but there are some differences between different types ofβ-blocker treatment,in the clinical course of medication to be considered,rational drug use.