The Multicenter Study of Fasudil on the Serum Level of C-reactive Protein and Homocysteine in Acute Cerebral Infarction Patients
Abstract：Objective:To explore the effects of Fasudil on the serum level of CRP and Hcy in acute cerebral infarction patients through the multicenter study.Method:96 patients with acute cerebral infarction admitted in neurology of A,B,C hospital were selected,and they were divided into the experimental group and the control group according to the random number table method,48 cases in each group.The control group was treated with routine therapy.The experimental group was treated with intravenous drip of Fasudil hydrochloride 30 mg once a time on the basis of routine therapy,twice daily,lasted for two weeks. The serum level of CRP and Hcy between the two groups before and after treatment were observed and compared.Result:The serum Hcy,CRP levels of two groups after treatment were significantly lower than before treatment,and the serum Hcy,CRP levels in experimental group were significantly lower than those in control group,the differences were statistically significant(P<0.05).Conclusion:The Fasudil can obviously improve the serum level of CRP and Hcy in the patients with acute cerebral infarction,improve the patients’neurologic deficits,and has the guidance significance for clinical,is worth the clinical promotion.
Keywords：FasudilAcute cerebral infarctionCRP levelHcy levelMulticenter study
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 7-8 )