The Clinical Observation of Tissue-type Plasminogen Activator for Intravenous Thrombolysis Combined with Edaravone in the Treatment of Acute Cerebral Infarction
CHEN Chun-yan
ZHANG Yan
LU Xue-sheng
Abstract：Objective:To investigate the clinical efficacy of rt-PA for intravenous thrombolysis combined with Edaravone in the treatment of acute cerebral infarction.Method:200 patients with acute cerebral infarction in our hospital from January 2010 to December 2013 were selected,they were divided into the group A,B,C and D according to the random number table method,50 cases in each group.The group A was given rt-PA for intravenous thrombolysis combined with Edaravone,the group B was given rt-PA for intravenous thrombolysis combined with conventional treatment,the group C was given Edaravone and conventional treatment,the group D was only given conventional treatment.The clinical efficiency of four groups were compared after 14 days treatment.Result:After treatment, the total effective rate of group A was 96.0%(48/50),it was significantly higher than the other three groups,the differences were statistically significant(P<0.05). The total effective rate of group B and group C were 84.0%(42/50) and 66.0%(33/50),respectively,which were significantly higher than 46.0%(23/50) of group D, and the total effective rate of group B was significantly higher than group C,the differences were statistically significant(P<0.05).Conclusion:Application of rt-PA for intravenous thrombolysis combined with Edaravone in the treatment of early acute cerebral infarction patients has the safety and effectiveness,can improve the prognosis of patients to the maximum extent,is worthy of clinical application and promotion.
Keywords：Acute cerebral infarctionrt-PAEdaravoneIntravenous thrombolysis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 3-4 )