The Clinical Efficacy of Glucocorticoid De-escalation Therapy in Chronic Eczema

ZHONG Qing-dong

Abstract：Objective:To observe the clinical efficacy of glucocorticoid de-escalation therapy in chronic eczema.Method:100 cases of chronic eczema in our hospital from February 2013 to April 2014 were selected for the study.According to randomly methods,they were divided into Compound Clobetasol Propionate Ointment group(control A group),Mometasone Furoate Ointment group(control group B) and Flufenamic Acid Ester Ointment group(control group C), and experimental group,25 cases of each group.The experimental group(25 cases) were given De-escalation therapy,medication followed Compound Clobetasol Propionate Ointment,Mometasone Furoate Ointment,Ointment Flufenamic Acid Ester Ointment.Treatment effects of each group were observed and statistically analyzed.Result:The difference between the experimental group and the control group A had no significant effect(P>0.05).The experimental group of treatment effect was significantly better than the control group B and C,there were statistical significance(P<0.05).The experimental group incidence of adverse reactions was significantly lower than the control group A(P<0.05).Conclusion:For patients with chronic eczema,de-escalation therapy is an ideal treatment plan,it is efficacy,fewer adverse reactions,should be introduced.