The Analysis of Curative Effect of Oxycodone Hydrochloride Prolonged-release Tablets in the Treatment of Cancer Pain by Rectally Administered
WU Han-bing
HU Chun-hong
Abstract：Objective:To observe the clinical effect and side effect of Oxycodone Hydrochloride Prolonged-release Tablets on cancer pain by rectally administered.Method:60 patients with moderate and severe cancer pain admitted to our hospital from April 2010 to February 2013 were selected,they were randomly divided into the experimental group and the control group,30 cases in each group.The two group were given Hydrochlorid Prolonged-release Tablets, the experimental group was given administered rectally,the control group was given administered orally,the NRS score of each time point,pain relief situation and adverse reactions between the two groups were observed and compared.Result:There were no statistically significant differences in the NRS score of two groups after medication at 1 h,3 h,1 day,1 week and 2 weeks and pain remission rate.In the experimental group,the incidence of nausea and vomiting in second degree or above was 10.00%,incidence of constipation was 20.00%,incidence of drowsiness was 10.00%,they were significantly lower than 40.00%,43.33%and 33.33%in control group group,the differences were statistically significant(P<0.05).Conclusion:The Hydrochlorid Prolonged-release Tablets administered rectally have the same analgesic effect as administered orally,but less side effects,it has a good clinical application value.
Keywords：Cancer painOxycodone Hydrochloride Prolonged-release TabletsRectally administrationClinical effect
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 7-8,9 )