The Diagnostic Yield of EUS-guided Holing Biopsy in Borrmann TypeⅣGastric Cancer

Abstract：Objective:To evaluate the diagnostic yield of EUS-guided holing biopsy in Borrmann type Ⅳ gastric cancer.Method:The clinical diagnose data of 53 cases of Borrmann type Ⅳgastric cancer patients who were confirmed pathologically by operation examination or gastroscopy were analyzed retrospectively.Result:The positive rate of first routine biopsy was 30.2%(16/53). The cases with negative first routine biopsies were treated with repeated biopsies(2-4 times),and the positive rate was 13.5%(5/37).The overall positive rate of gastroscopic routine biopsy was 39.6%(21/53).46 cases were diagnosised by EUS,and the coincidence rate in diagnosing Borrmann type IV gastric cancer was 95.5%(44/46).The cases with negative gastroscopic routine biopsy were treated with EUS-guided holing biopsys,and the positive rate was 61.9%(13/21). Minor bloods oozing in 2 patients were controlled by epinephrine. Neither severe hemorrhage nor perforation was founded in any cases. Conclusion:EUS-guided holing biopsy has superiority of raising the positive rate of gastroscopic biopsy. It is an effective technique to diagnosis Borrmann typeⅣgastric cancer with pathological basis. And the technique is safety and inexpensiveness.