Expression of Her-2 in Stomach Cancer and Its Relationship with Clinical Staging
LING Hang
YU Xun-bin
Abstract：Objective:To explore the expression of Her-2 in stomach cancer and its relation with clinical staging.Method:273 cases of lung cancer in our hospital were selected,then detected the expression of Her-2 in tumour tissues and normal tissues by immunohistochemistry stain and compared the results.Result:The positive rate of Her-2 protein in tumour tissues was 26.58%,which was significantly higher than that in gastric mucosa 0%,the difference was statistically significant(P<0.05).Besides,the suspected positive rate of Her-2 in tumour tissues was significantly higher than that in gastric mucosa(P<0.05). The statistics showed that the positive Her-2 expression in IV stage was 64.29%,which was significantly higher than stageⅢ,Ⅱ,Ⅰ,and the differences were statistically significant(P<0.05),with the reduce of staging level for lung cancer,the positive of Her-2 had reduced,which showed positive correlation between them.Conclusion:The expression level of Her-2 in lung cancer tissues is significantly higher than normal gastric mucosa,and it has positive correlation with cancer staging.
Keywords：Lung cancerHuman epidermal growth factor receptor-2ImmunohistochemicalClinical staging
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 53-54 )