The Clinical Efficacy of Metformin for Gestational Diabetes

XU Xiao-ling

Abstract：Objective:To explore the clinical efficacy and evaluate its safety of metformin for gestational diabetes.Method:126 patients were divided into control group and observation group with gestational diabetes according to the patient’s admission in accordance with the order of the random number table randomly,63 cases in each group. The control group was treated with Novolin 30R,and observation group was treated with metformin during pregnancy ends. Result:After treatment,fasting and 2 h postprandial blood glucose decreased significantly than before treatment (P<0.05). The difference between the fasting glucose and postprandial 2 h was not statistically significant in the two groups before giving birth (P>0.05). When to childbirth,weight gain of pregnant woman in observation group was (1.02±0.73) kg,which was significantly lower than that in the control group’s (2.13±0.76) kg. The incidence of hypoglycemia in the observation group and a huge proportion of children were significantly lower than the control group(P<0.05).Conclusion:The metformin has a curative effect on the treatment of gestational diabetes,and not increase the risk of maternal and clinical safety.