Dexmedetomidine Reducing Sufentanil Induced Cough during Children General Anesthesia Induction
ZHANG Cheng
XU Xiao-yan
Abstract：Objective:To observe the effects of Dexmedetomidine in reducing children cough induced by Sufentanil in general anesthesia induction. Method:Our hospital from May 2011 to November 2013,60 children undergoing elective operation,the pediatric patients were randomly divided into control group and experimental group,30 cases in each group.15 min before experimental group constant rate intravenous infusion of Dexmedetomidine,the control group constant rate intravenous infusion of saline infusion pump,15 min.Pump after the end of the two groups were intravenous injection of Propofol 2 mg/kg with Sufentanil 0.5 μg/kg and Vecuronium 0.1 mg/kg anesthesia induction.During the maintenance of anesthesia with Propofol and Remifentanil.Observation of intravenous Sufentanil post to 5 min cough frequency and hemodynamic changes.Result:The hemodynamic changes of two groups were compared,there were no significant differences,but the rate and degree of cough in the experimental group were significantly better than the control group(P<0.05).Conclusion:The induction period of Sufentanil induced cough suppression of Dexmedetomidine can effectively general anesthesia.
Keywords：DexmedetomidineSufentanilCoughChildrenGeneral anesthesia
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 8-9,10 )