Effect of Acute Decompensated Heart Failure Patients with Valsartan and Influence on Serum CardiacTroponin T and High Sensitive C Reactive ;Protein

LIN Qing-shan

Abstract：Objective:To observe the effect of valsartan in acutedecompensated heart failure (ADHF) in patients with clinical efficacy as well as to the blood center in patients with cardiac troponin T(cTnT) and high sensitive C-reactive protein(hs-CRP) content influence.Method:76 case of patients with acute decompensated heart failure were treated in author’s hospital,were randomly divided into valsartan group and control group,38 cases in each. The control group received routine treatment,valsartan group was treated with valsartan in the treatment ofobservation period,and mortality,heart failuredeterioration rate and the number of iterations,ICU ward hospitalization,adverse reactions were compared between two groups of patients,and to detect changes in two groups of patients cTnT,hs-CRP.Result:Valsartan group patients in the ICU ward hospitalization time was less than that in the control group,the difference was statistically significant(P<0.05). Comparison of two groups of patients before treatment,blood cTnT and hs-CRP levels were significantly decreased,the difference was statistically significant(P<0.05);and valsartan group was lower than the control group,the difference was statistically significant(P<0.05).Conclusion:At the same time the routine treatment plus valsartan,repetition can significantly reduce heart failure in patients with ADHF,shorten the time ofhospitalization in patients with ADHF,its pharmacological mechanism may be valsartan can significantly reduce cTnT and CRP level in the serum of patients with.