Analysis of Clinical Distribution and Drug Resistance of 285 Strains of Invasive Fungal Infection
Abstract：Objective:To understand the clinical distribution and drug resistance status of invasive fungal infections.Method:To retrospective analysis the flora distribution and drug resistance characteristic of 285 strains of invasive fungi in our hospital from January 2012 to December 2013.Result:The highest rate of was Candida albicans strains in 285 strains of fungi which was 219 strains,accounted for 76.84%.The most sensitive of 5 kinds of Candida on 5-fluorocytosine and amphotericin B were above 95.4%and 76.9%,sensitivity of Candida albicans to 5-flucytosine,Amphotericin B and Fluconazole,Voriconazole reached over 94.1%,but the sensitivity rate to itraconazole was only 46.1%,Candida glabrata and Candida krusei resistant to Itraconazole rate was 100%.The resistances of Nearly smooth Candida albicans and Candida tropicalis to Fluconazole were respectively 68.2%and 33.3%.Conclusion:Fungal culture and drug sensitivity test are important for rational use of antifungal drugs,and they can guide the clinical significant.
Keywords：Invasive fungal infectionDrug sensitivity testDrug resistance analysis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 57-58,59 )