Analysis of the Serum Levels of Immunoglobulins A,G,M and T Lymphocyte Subgroup in Children with Recurrent Pneumonia
XIAO Hai-ni
Abstract：Objective:To investigate the changes in serum Immunoglobulins and T lymphocyte subgroup in children with recurrent pneumonia,and the role of immune function testing in recurrent pneumonia.Method:The expressions of Immunoglobulin and T lymphocyte subgroup were detected by rapid immune turbidimetry and flow cytometry in recurrent pneumonia children and healthy children(Control group).Result:The levels of IgG,IgA were all significantly lower in recurrent pneumonia children than those of control group(P<0.01),there were no significant differences in the levels of IgM between two groups(P>0.05).Meanwhile the percentage of CD4+cell and the ratio of CD4+/CD8+were also all significantly lower in recurrent pneumonia children than those of control group(P<0.01),but the percentage of CD8+cell was significantly higher in recurrent pneumonia children than those of control group(P<0.01).Conclusion:There are disfunctions of cellular immunity and humoral immunity in recurrent pneumonia children,which may contribute to the pathogenesis in children with recurrent pneumonia.
Keywords：Recurrent pneumoniaChildrenImmunoglobulinT lymphocyte subgroupHumoral immunityCellular immunity
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 56-57 )