The Intrauterine Insemination Outcome of PCOS Patients by Different Stimulate Ovulation

Abstract：Objective:To compare the intrauterine insemination(IUI) outcome of PCOS patients by different stimulate ovulation,to find out the best stimulate ovulation.Method:161 cases of PCOS who cycle underwent in intrauterine insemination.They were divided into clomiphene(CC) group(group A), CC+HMG group(group B),HMG group(group C) according to personal willingness.The clinical data and the outcome of the three groups were compared. Result:There were no significant difference among the three groups in patients’ average age,infertility,the number of mature follicle,the clinical pregnancy rate and the incidence of OHSS,multiplets rate(P>0.05),but the highest clinical pregnancy rate was group B,the hCG day endometriums was thinner and the abortion rate was higher in group A than those of the other two groups(P<0.05).Comparing group C and group B,the less Gn days and the small Gn dosage in group B than that of group C,the differences were statistically significant(P<0.05).Conclusion:All three stimulate ovulation scheme are applicable to patients with PCOS,The CC+HMG group can be used as first choice for high clinical pregnancy rate and low abortion rate,the less Gn days and the small Gn dosage.