Analysis of Serum Thyroid Hormone Levels in the Three Trimester of Normal Pregnancy Woman

Abstract：Objective:To investigate the change characteristics of the serum thyroid hormone levels in the three trimester of normal pregnancy women Method:The serum free triiodothyronine (FT3),free thyroxine (FT4) and thyroid stimulating hormone (TSH) levels was measured using automated chemiluminescence immunoassa in Shenzhen area of 860 cases pregnant women and 209 cases healthy non-pregnant women,which 308 cases of early pregnancy, 315 cases of the second trimester,the third trimester of 237 cases,and make the statistical analysis. Result:The FT3,FT4 levels of the early pregnancy group,the second trimester group and the third trimester group gradually decreased,comparing with the non-pregnant group,the difference was statistically significant (P<0.05). The TSH levels drop in the early pregnancy and the second trimester group,comparing with non-pregnant group,the difference was statistically significant (P<0.05). The TSH levels in the third trimester group returned the level when non-pregnant,comparing with early pregnancy and the second trimester group ,the difference was statistically significant (P<0.05) .Conclusion:The thyroid hormone levels of women in the early pregnancy ,the second trimester and the third trimester differ from non-pregnant women,regular testing of the thyroid hormone levels is recommended during pregnancy,so that early detection and early treatment,thereby reducing the maternal and fetal harm.