Study of Cytokines in Sera of Patients with Cystitis Glandularis in IL-2,IFN- γ,TNF-α

CUI Ying-dong; HU Shu-bin

Abstract：Objective:To investigate the role of the cytokines IL-2,IFN-γ,TNF-αin cystitis glandularis occurred. Method:Selected the author’s hospital treated by cystoscopy and biopsy was confirmed pathologically as cystitis gland sex as experimental group of 30 cases,alternate period health check-up 30 cases as control group,through the detection of the expression levels of two groups of patients with serum IL-2,IFN-γ,TNF-αcytokine,and expression level in the patients with cystitis glandularis after 3 months of treatment the serum levels of IL-2,IFN-γ,TNF-αcytokine,make statistical analysis. Result:Treatment group 28 cases effective,2 cases had no effect,the effective rate was 93.3%. Patients serum cytokine IL-2,IFN-gamma,TNF alpha were significantly higher than that of control group,the difference was statistically significant (P<0.05). But the experimental group before and after treatment serum cytokine IL-2,IFN-gamma,TNF alpha comparison difference had no statistical significance (P>0.05).Conclusion:Cytokines in the gland sex cystitis plays an important role;cutting and bladder perfusion chemotherapy drugs in treatment of glandular cystitis method does not change cytokines in serum IL-2,IFN-γ, TNF-αlevel,patients need long-term follow-up.