Effects of Adjuvant Chemotherapy on Locally Advanced Nasopharyngeal Carcinoma after Periodic Radiotherapy

GAO Tian-sheng

Abstract：Objective:To explore and study the effect and clinical value of adjuvant chemotherapy on locally advanced nasopharyngeal carcinoma after the periodic radiotherapy.Method:100 cases with locally advanced nasopharyngeal carcinoma in our hospital were randomly chosen and divided into two groups by therapeutic methods:chemoradiotherapy group(A group,n=50),patients were treated with radiotherapy,combined group(B group,n=50),patients were treated with adjuvant chemotherapy after radiotherapy,concurrent chemotherapy and radiotherapygroup+adjuvant chemotherapy group.Then the status of two groups after treatment were observed,with comparations and studies.Result:A group of patients with neutropenia,occurring skin reactions,nausea,vomiting,and anemia risk of adverse reactions were significantly lower than combined group,and the difference was significant,it had statistically significant(P<0.05);B group of five-year survival of rate was significantly higher than A group,the difference was significant,it had statistical significance(P<0.05).Conclusion:Taken at the same time concurrent chemoradiotherapy for adjuvant chemotherapy in patients with locally advanced nasopharyngeal carcinoma,can effectively improve the five year survival rate of patients ,make more effective treatment,it has very important value in clinical application.