Analysis of Two Different Methods in the Diagnosis of Hemolytic Disease of the Newborn
YANG Pei-ke
BU Xiang-mao
Abstract：Objective:To investigate the efficacy of acid elution and frozen-thawed elution test in detecting hemolytic disease of the newborn caused by ABO incompatibility.Method:209 cases of blood samples from newborns with hyperbilirubinemia were collected.Antibody molecules bound to red blood cell membrane were released by acid elution test or frozen-thawed elution test respectively.Then the difference and consistency with clinical diagnosis between two methods were analyzed.Result:In the group of using acid elution method,64 cases were positive(positive rate,30.62%),and 63 cases were positive in frozen-thawed elution group(positive rate,30.14%).There was no significant difference between two methods(P>0.05).However,the degree of positivity with acid elution was stronger than with frozen-thawed elution.Conclusion:Acid elution is a better method in diagnosing hemolytic disease of the newborn caused by ABO incompatibility.
Keywords：NewbornABO hemolytic diseaseFrozen-thawedAcid elution
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 66-67 )