The Observation of the Clinical Efficacy of Liraglutide in Type 2 Diabetes

WU Lei; PAN Wei-bin

Abstract：Objective:To observe the efficacy and safety of Liraglutide in type 2 diabetes.Method:Selected the author’s hospital treated 150 cases of patients with type 2 diabetes,according to the principle of random divided into five groups of intervention in the treatment group,30 cases each,respectively, to give metformin and gliclazide,nateglinide,insulin,liraglutide treatment. Another 30 cases of healthy physical examination were selected as control group and observation group before and after treatment 1 year six groups mass index (BMI),systolic blood pressure (SBP),diastolic blood pressure (DBP),fasting blood glucose (FBG),2 h postprandial blood glucose (2 h PBG),glycosylated hemoglobin (HbA1c),triglycerides (TG),total cholesterol (TC),low density lipoprotein (LDL-C),high density lipoprotein (HDL-C),and other indicators.Result:The liraglutide group after treatment of BMI,FBG,compared with before treatment, the difference was statistically significant (P<0.05),2 h PBG and HbA1c decreased obviously,compared with before treatment,the difference was statistically significant (P<0.01),TG,TC and LDL-C fell,but there was no statistically significant difference compared with before treatment (P>0.05). The lalu peptide group of severe hypoglycemia.Conclusion:Liraglutide has better efficacy and safety in type 2 diabetes mellitus.