The Positive Rate Analysis of Syphilis Antibody Detection in 12 103 Cases

Abstract：Objective:To analyze and further discuss the positive rate of syphilis in old patients by method of Enzyme-linked immunosorbent assay (ELISA) and treponema pallidum particle assay(TPPA) test. Method:A total of 12 103 outpatient and hospitalized patients tested by ELISA were selected,and they were divided into the control group(<60 years,n=9145) and the elderly group(≥60 years,n=2158),and the positive specimens applied TPPA test further.The differences of the positive rate and the positive coincident rate of the two groups in the two methods were respectively analyzed. Result:The positive rates of the two methods were compared,and the difference was statistically significant(X2=22.04,P<0.05).The positive rates of two age groups in the two methods were compared, and the differences were statistically significant(TP-ELISA:X12=28.64,P1<0.05;TPPA:X22=18.83,P2<0.05).The positive cases confirmed by TPPA were 71 cases and 116 cases,and the positive coincident rate were 83.53%and 91.34%respectively. The positive coincident rates of the two age groups were compared,and the difference was statistically significant.Conclusion:The detectable rates of the two methods are different.The positive rate of the elder is higher than that of the young.The positive coincident rate of the elder was higher than that of young.Therefore,the clinical diagnosis should combine other methods to reduce the error and promote the detection rate and accuracy of treponema pallidum.