Clinical Significance of Blood Biochemical Tests for Hypoxic-ischemic Encephalopathy
ZHANG Ming-ying
KANG Xu-li
Abstract：Objective:To explore the change and their clinical significance of K+,Na+,Cl-,Ca2+ and glucose in serum of hypoxia-ischemic encephalopathy(HIE).Method:Testing 165 serum samples from HIE and 35 serum samples from normal neonatal for K+,Na+,Cl-,Ca2+,glucose in order to compare with each other.Result:Na+and Ca2+in serum decrease obviously and K+increased in HIE group,the difference between two groups was statistically significant(P<0.05);But the Cl-level had no significant change(P>0.05).Different degree of HIE and the decrease of Na+and Ca2+had significantly positive correlation and r=0.841(P<0.05),0.654(P<0.05).Hypoglycemia much more happened in mild and moderate HIE,the incidence of hyperglycemia increased with the clinic degree of HIE.Conclusion:Children with HIE can appear low level of Ca2+,Na+and high level of K+and glucose metabolic disorder.The more serious of HIE degree,the lower are Ca2+,Na+in blood,which are significantly positive correlation with increased incidence of hyperglycemia.Above results indicate that the K+,Na+,Ca2+and glucose in blood have certain clinical significance to justice the degree of HIE and its prognosis.
Keywords：Hypoxic-ischemic encephalopathyElectrolyteBlood glucose
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 1-2 )