Clinical Observation of Mifepristone in Late Pregnancy Labor Induction

Abstract：Objective:To investigate the feasibility of mifepristone with oxytocin induction of labor in late pregnancy. Method:Select the author’s hospital treated late pregnancy (intrauterine pregnancy after 28 weeks) with fetal malformation,fetal intrauterine fetal death,premature rupture of membranes merger intrauterine oligohydramnios,122 cases of patients.The reasearch group (62 cases),no matter whether the cervical mature to 100 mg of single oral mifepristone to oxytocin intravenous drip induced labor at the same time,the control group (60 cases),such as cervical prasterone immature to intravenous to oxytocin static drop induced labor at the same time,the cervical mature to oxytocin static drop induced labor directly.24 h induced labor unsuccessful team repeated use 100 mg single oral mifepristone and control group in the cervical prasterone immature reuse intravenous injection,two groups of intravenous drip oxytocin oxytocin until fetal childbirth,compared two groups under different cervical maturity amount induced labor time,use of oxytocin,postpartum blood loss and soft birth canal injury. Result:Two groups of 122 patients were successfully induced labor,cervical mature and immature in both cases the team in induced labor time,oxytocin usage were superior to control group,the difference was statistically significant (P<0.05) in cervical Bishop score,postpartum hemorrhage and soft birth canal injury,the more similar between the two groups had no statistical significance (P>0.05).Conclusion:Mifepristone combined with oxytocin might effectively shorten the labor induction time and improve the efficiency of labor induction without the increasing of the amount of postpartum hemorrhage and soft birth canal injury and be worthy of promotion.