The Observation of Dezocine on Prevention and Treatment of Emergence Agitation after General Anesthesia Operation
TANG Ai-ping
CHEN Jin-bao
Abstract：Objective:To investigate the efficacy and safety of dezocine on prevention of emergence agitation in adult patients during recovery period after general anesthesia.Method:Sixty patients,ASA Ⅰ or Ⅱ,undergoing Laparoscopic cholecystectomy(LC) were randomly divided into two groups, experimental group and control group.15 min before the end of surgery,a bolus of dezocine 0.1 mg/kg or 1 ml saline was given,the incidence of emergence agitation,restlessness and sedation scale,extubate and recovery time,emergence agitation anesis,and adverse events were evaluated.Result:The incidence of emergence agitation was significantly higher in control group than that in experimental group(P<0.05).The sedation scale was higher in experimental group,but there were without excess sedation and palinesthesia delayed.When another bolus was administer-ed intravenous,the emergence agitation remitted significantly in experimental group 5/5(100%)and control group 15/20(75.0%),and there was no respiratory depression in two groups.Conclusion:Benefit from the analgesic and sedative property of dezocine,it could be one of the ideal drugs to prevent and relieve emergence agitation in the patients after general anesthesia with less frequent adverse events.
Keywords：DezocineGeneral anesthesiaRecovery periodEmergence agitation
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 3-4 )