Pathological Analysis of Diabetic Nephropathy and Non-diabetic Renal Disease in Patients with Type 2 Diabetes Mellitus
ENG Li
WANG Yan
Abstract：Objective:To analyze the type 2 diabetic patients with clinical manifestation and pathological results,and to investigate the importance of renal biopsy on the diagnosis of diabetic nephropathy(DN).Method:Renal biopsy specimens were obtained from 61 patients with type 2 diabetes mellitus with albuminuria ,analyze their clinical markers and pathological results.Result:Among 61 cases,32 patients(52.5%) were DN,29 cases(47.5%) were (NDRD).The diabetic course,hematuria from glomerulus of kidney,diabetic retinopathy were significantly different(P<0.05),other markers had no significantly differences. IgA nephropathy was the most common,accounting for 31.0 % of group NDRD,membranous nephropathy ranked second accounting for 17.2 %,followed by mesangial proliferative nephritis 13.8%,hypertensive nephrosclerosis 13.8%,FSGS 10.3%,minimal change disease 6.9%,crescentic GN 3.5%,renal amyloidosis 3.5%.Conclusion:The present study showed that IgA nephropathy is the commonest NDRD among diabetics.Diabetic retinopathy and hematuria from glomerulus of kidney are important factors for diagnosing diabetic nepropathy.When we have no enough evidence to prove DN in clinical,renal biopsy is an important tool to distinguish and diagnosis NDRD and DN.
Keywords：Type 2 diabetes mellitusDiabetic nephropathyNon-diabetic renal diseaseRenal biopsy
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 7-8,9 )