The Pathogen Detection and Clinical Treatment for the Intracranial Infection after Craniotomy or Head Trauma
Abstract：Objective:To provide the basis for the clinical treatment,researchers used the pathogen test and the drug-susceptibility test in patients with intracranial infection after Craniotomy or head trauma.Method:Cerebrospinal fluid from 55 patients with intracranial infection after craniotomy or head trauma, who had been in the hospitals from January 2008 to Jan 2013,were examined.Bacterial aerobic culture and drug-susceptibility test were performed by using the automatic bacterial analysis system.Result:A total of 110 copies of cerebrospinal fluid achieved by 55 patients,51 cases were positive(46.36%),46 pathogens were isolated,33 cases was Gram-positive bacteria (71.74%),12 cases was Gram-negative bacteria(26.09%),one case was fungi(2.17%).The top five pathogen were coagulase-negative staphylococci in 25 cases(54.35%),Staphylococcus aureus in 5 cases(10.86%),Enterobacter in 3 cases(6.52%),Acinetobacter in 3 cases(6.52%),Pseudomonas aeruginosa in 2 cases(4.35%).Fivty-five cases were efficient significantly in 55 patients,2 patients were discharged,and 2 patients were dead(3.63%).Conclusion:Detecting pathogens timely,diagnosing early and giving antibiotics efficient and sensitive by the combination of intravenous and intrathecal can improve the cure rate and shorten the course of treatment effectively.
Keywords：Intracranial infectionPathogensDrug-susceptibility testingIntrathecal administration
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 6-7,8 )