The Clinical Research on Non-invasive Positive Pressure Ventilation Jointed Atomization Inhalation of Combivent Treated Severe Bronchial Asthma

Tang Qiu-jing

doi:10.3969/j.issn.1674-6805.2013.29.006

Abstract：Objective:To explore the clinical curative effect that non-invasive positive pressure ventilation jointed atomization inhalation of combivent treated severe bronchial asthma.Method:90 patients were randomly divided into treatment group and control group,which had been diagnosed as severe bronchial asthma in the Respiration Department of our hospital from June 2011 to January 2013. Each group contained 45 patients. The methods of treatment in control group were routine treatments,such as using oxygen,anti-infection,glucocorticoid,spasmolysis,relieving asthma and reducing phlegm. Excepting the routine treatments,treatment group also added non-invasive positive pressure ventilation jointed atomization inhalation of combivent. we observed the clinical effects in two groups. In addition,we recorded the changes of respiratory rate and the indexes of blood gas analysis before the therapy and after 6 hours of the therapy.Result:The effective rate in the treatment group was significantly higher than in the control group(P<0.001). The changes of respiratory rate and the indexes of blood gas analysis between the two groups before the therapy were not significant(P>0.05). However,after 6 hours of the therapy,respiratory rate and PaCO2 in treatment group were significantly lower compared to control group(P<0.05). On the contrary,PaO2 and SaO2 were significantly higher in treatment group (P<0.05).Conclusion:Non-invasive positive pressure ventilation jointed atomization inhalation of combivent have an obviously positive effect in the therapy of severe bronchial asthma,and need further promotion and application in the clinical work.