Clinical Observation of Docetaxel and Oxaliplatin on Advanced Non-small Cell Lung Cancer
WEI Rong
LI Qin
Abstract：Objective:To observe clinical efficacy and adverse reactions of advanced non-small cell lung cancer by docetaxel and oxaliplatin.Method:68 cases of non-small cell lung cancer patients were randomly divided into two groups.Observation group(34 cases) treated by docetaxel combined with oxaliplatin, control group(34 cases) treated with cisplatin combined with docetaxel,comparing curative effect observation.All the patients completed 2 cycles of drug using. Result:Observation group total effective rate(CR+PR) was 47.1%,control group total effective rate(CR+PR) was 41.2%,there was no statistically significant difference(P>0.05).Adverse reactions in two groups,nausea and vomiting observation group was obviously lower than the control group(P<0.05).Conclusion:For advanced non-small cell lung cancer patients,the use of oxaliplatin into joint docetaxel group and use cisplatin plus docetaxel group,curative effect is similar,but the use of oxaliplatin into group can effectively improve the patient’s clinical symptoms,the adverse event is lighter,is worthy of clinical promotion chemotherapy regimens.
Keywords：OxaliplatinDocetaxelCisplatinNon-small cell lung cancer
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1-2,3 )