The Clearance Effects of Hemoperfusion Combined with Hemodialysis on Macromolecular Toxins
JIN Li-xin
Abstract： Objective:To explore the clearance effects of hemoperfusion(HP) combined with hemodialysis(HD) on macromolecular toxins.Method:Sixty-five patients with uremic admitted by our hospital were randomly divided into hemodialysis(HD) group and hemoperfusion combined with hemodialysis(HP+HD) group.Both groups were given a regular hemodialysis program,while only the HP+HD group received hemoperfusion additionally.The levels of regular macromolecular toxins in blood of beta-2 microglobulin(β2-MG),leptin(LEP) and parathyroid hormone (PTH) were analyzed before and after treatment as well as the clearance rate.Result:The levels of β2-MG,LEP and PTH in both groups before treatment were lower than those after treatment(P<0.05).The above indicators of HP+HD group were lower than those of HD group(P<0.05),while the clearance rates of HP+HD group were superior to those of HD group(P<0.05).Conclusion:The clearance effects of hemoperfusion combined with hemodialysis was better,worth being promoted in the treatment of uremic.
Keywords：HemoperfusionHemodialysisUremiaBeta 2-microglobulinLeptinParathyroid hormone
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 8-9 )