Effect of Active Vitamin D3 on the Levels of Micro-inflammation in Patients with Maintained Hemodialysis
LUO Yuan-biao
ZENG Lei
HUANG Shao-zhen
Abstract： Objective:To investigate the effect of active vitamin D3 on the levels of micro-inflammation in patients with maintained hemodialysis. Methods:Sixty patients with maintained hemodialysis were assigned to history control group(n=30) and treatment group(n=30).Both of them treated with routine medicine treatment,while the treatment group added active vitamin D3,2μg per time,2 times per week.The treatment lasted for 12 weeks.The levels of high-sensitivity C-reactive protein,interleukin-6,tumor necrosis factor-αwere measured before and after treatment.Results:The levels of hs-CRP,IL-6 and TNF-α were decrease in both groups after treatment(P<0.05).Compared with the control group,the treatment group had better therapy outcomes(P<0.05). Conclusion:Active vitamin D3 can reduce the level of hs-CRP,IL-6 and TNF-α,therefore down-regulate the micro-inflammation in patients with maintained hemodialysis.
Keywords：Maintained hemodialysisMicro-inflammationActive vitamin D3
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 4-5,6 )