The Expression of Transforming Growth Factor Beta in Early Pregnancies Decidual Tissue Influenced by Mifepristone Compatibility Misoprostol Therapy
DU Chun-yan
ZENG Xue-hua
FAN Xiao-ming
Abstract： Objective:Through the research of mifepristone compatibility misoprostol therapy influenced the expression of transforming growth factor beta in early pregnancies decidual tissue,to discuss the function mechanism of termination of the early pregnancy therapy by mifepristone compatibility misoprostol. Methods:41 cases early pregnancy decidual tissue were collected from August 2010 to May 2011 in our hospital women outpatients,21 cases were divided into drug-abortion group,20 cases were divided into abortion group,then detected the expression of transforming growth factor beta.Results:The expression of drug-abortion group had statistically significant with abortion group(P<0.05),drug-abortion group expression was low,and had large difference of expression level. Conclusion:Mifepristone can reduce the expression of transforming growth factor beta,which can terminate pregnancy through the immune effect,misoprostol can enhance the effect or independent play the effect of termination of pregnancy.
Keywords：MifepristoneMisoprostolDecidual tissueTransforming growth factor beta
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 6-7 )