Curative Effect Observation on Sex Hormones and Insulin Level of Patients with Polycystic Ovary Syndrome and Insulin Resistance by Traditional Chinese Medicine

LI Shu-hong; QIN Xiao-bo

doi:10.3969/j.issn.1674-6805.2013.19.002

Abstract： Objective:To study traditional Chinese medicine treatment for insulin resistance polycystic ovary syndrome(PCOS-IR) patients clinical treatment effect and the determination of hormones and insulin level of change.Methods:A total of 92 patients with PCOS-IR were randomly divided into observation group and control group,each group of each 46 cases.The comparison group used the metformin drug therapy,the observation group took western medicine again on the basis of the kidney and liver,spleen qi of traditional Chinese medicine treatment;Two groups were treated for 4 months. At the same time testing the two groups before and after treatment serum sex hormones and insulin levels and changes of two groups of patients in clinical outcomes,complications and adverse reaction of comparative analysis.Results:Two groups of patients after treatment,serum luteinizing hormone(LH), testosterone(T),fasting insulin(F-INS) level was before treatment greatly decreased significant difference(P<0.01);The observation group LH,T and F-INS down level was slightly larger group,but there was no significant difference(P>0.05);Two groups of patients serum FSH/FBG level were no significant difference(P>0.05).Clinical effects of patients with compared to control group,the efficient was obviously higher than those in the control group,the difference was statistically significance(P<0.05);Two groups of patients in the treatment process all did not appear serious complications and adverse reaction phenomenon.Conclusion:The combined traditional Chinese and western pharmaceutical application in the treatment of PCOS patients by obvious effect,can reduce serum LH,T,F -INS,increase the level of insulin sensitivity,improve clinical symptoms,improve the ovulation rate and pregnancy rate.Therapeutic thoroughly,no special complications of disease and adverse reaction characteristics,can be used as in PCOS patients by the preferred method of treatment.